The RDT tests are still regarded as complements to conventional microscopy but with some improvements it may well replace the microscope.

Their instrument theoretically could resolve structures 1.75 times smaller than conventional confocal microscopy.

Thus, the resolution limit is usually around λ/2 for conventional optical microscopy.

But it reveals internal details in their natural condition without the disruption that preparation for conventional microscopy usually entails.

As opposed to conventional microscopy, HRTEM does not use amplitudes, i.e. absorption by the sample, for image formation.

This can provide higher spatial resolution beyond the limitations imposed by the law of diffraction in conventional far-field microscopy.

The outermost domain in the kinetochore forms a fibrous corona, which can be visualized by conventional microscopy, yet only in absence of MTs.

These can be then assessed on a computer screen similar to conventional microscopy, allowing the pathologist to maneuver around the image and view every part of the slide at any magnification.

RESOLFT microscopy is an optical microscopy with very high resolution that can image details in samples that cannot be imaged with conventional or confocal microscopy.

Due to the narrow focal depth of conventional microscopy, live cell imaging is to a large extent currently limited to observing cells on a single plane.