Such clones are not strictly identical since the somatic cells may contain mutations in their nuclear DNA.

Genotype of cells - Cloning strains may contain mutations that improve the transformation efficiency of the cells.

A randomly evolving DNA sequence contains mutations with no effect on the fitness and survival of an organism.

This condition is inherited in an autosomal recessive fashion, meaning that the two copies of the gene in every cell contain mutations.

If the combination of two genomes containing different recessive mutations yields a mutant phenotype, then there are three possibilities:

But it always contained its own potential perversions and mutations.

As is probably true for everyone, their genomes are likely to contain mutations that could lead to disease, revealing possibly unfavorable information about themselves and their relatives.

The leukemic cells contained acquired mutations in several genes that had not previously been associated with the disease.

Autosomal recessive inheritance, where both copies of a gene contain mutations, is especially associated with C5-C6 fusion.

When comparing the two sequences these researchers discovered 10 genes which contained acquired mutations: