Antihistamines competitively bind to histamine receptor sites, thus reducing the neurotransmitter's effects.

Antihistamines act by competitively binding to H1- receptor sites, thus blocking the binding endogenous histamine.

Alvimopan competitively binds to mu-opioid receptor in the gastrointestinal tract.

It does this by binding to and competitively inhibiting the transpeptidase enzyme used by bacteria to cross-link the peptide (-alanyl-alanine) used in peptidoglycan synthesis.

Competitively binds calcium ions (Ca)

It is a mixed agonist/antagonist, binding competitively to rat uterine estrogen receptors, though with a very low binding affinity of 1/300.

Tamoxifen and several of its metabolites competitively bind to estrogen receptors on tissue targets, producing a nuclear complex that decreases DNA synthesis.

Volasertib is a novel small-molecule targeted therapy that blocks cell division by competitively binding to the ATP-binding pocket of the PLK1 protein.

The most common antiandrogens are androgen receptor (AR) antagonists which act on the target cell level and competitively bind to androgen receptors.

Astemizole competitively binds to histamine H1-receptor sites in the gastrointestinal tract, uterus, blood vessels, and bronchial muscle.