My biggest breakthrough during the first six months came in the flexibility department.

"Somehow, at least on paper, it looks like we have made a big breakthrough."

Their meeting is unlikely to result in any big breakthroughs.

She thought I was talking about some big breakthrough in our business discussions.

One big breakthrough and then a thousand ways to follow up on it.

The first big breakthrough came in 1985 when the Titanic was discovered under 2.5 miles of water.

This could be a big breakthrough in romance for her.

The project predicted that their big breakthrough, would come in 1990.

I want to remind you that together we have made a big breakthrough.

The thing about a designer's big breakthrough is that it can happen only once.