When these cells are infected with a virus (or another intracellular pathogen), the cells degrade foreign proteins via antigen processing.

This pattern of expression reflects their role in foreign antigen processing and recognition by T cells.

The peptide translocation from the cytosol into the lumen of the ER is accomplished by the transporter associated with antigen processing (TAP).

Transporter associated with antigen processing (TAP) is a member of the ATP-binding-cassette transporter family.

In contrast, the B cell antigen-specific receptor is an antibody molecule on the B cell surface, and recognizes whole pathogens without any need for antigen processing.

Early lytic gene products have many more functions, such as replication, metabolism, and blockade of antigen processing.

Together, Unanue & Askonas made the seminal observation that macrophages did not completely catabolize antigens, foreshadowing development of the field of antigen processing and presentation.

Unanue's current research focuses on the molecular mechanisms of antigen processing, the immunological basis of autoimmune diabetes, and immune responses to intracellular bacteria.

Transporter associated with antigen processing ("TAP")

Cross-priming avoids viral immune evasion strategies, such as suppression of antigen processing.