"Maybe the problem is coming from an altogether different place."

Those women could have told the same story for an altogether different reason.

I am here to say the truth is altogether different.

"Now I have another question of an altogether different nature to ask you."

Here the changes are more significant still, but for altogether different reasons.

As a young man, I tried to create a life for myself that was altogether different from my father's.

"Actually parents say one thing and do something altogether different," he said.

Because whatever they had done, he would have to do something altogether different.

Then again, maybe it would have an altogether different effect.

"It's that all the companies are altogether different from one another."