Her special interest was the science of color, then in significant development.

The area has been a site of significant economic development in recent years.

But that was not the most significant development of the game.

This was a period of significant development in the church.

"This is a significant development but not the end of the game."

Later significant development occurred in 1958-60 and during the 1980s.

Which leads us to the most significant development of a season that began last night.

The city has seen significant development since China's reform and opening began.

Despite this significant development, there is still potential for progress.

This was useful, since the Il-62 did call for significant development.