It's early, but we may be at the start of a significant political advance.

Over the course of time, the University has made significant advances in its academic programs.

Researchers have made a number of significant advances in the past few years.

From the turn of the 20th century, however, there had been a significant advance in industrial development.

Private banking has made significant advances in the last year.

"This is certainly the most significant advance within our lifetime."

American officials have praised the vote as a significant advance.

I don't think making the distinction is a significant advance in its understanding.

The most significant advance, however, lies in video on demand.

It was frustrating to see some of our significant advances taken away.