However, at the beginning of the 1970s, profound changes took place.

But the energy bill would make profound changes in other areas as well.

In the last few minutes a profound change had come over him.

People understand they are living in a period of profound change.

He will give a little more space to the church but profound changes?

The health care system is certainly going through profound change.

She told me that everyone expected profound changes in political life.

Now we are in a time of profound change and opportunity.

I would like you, with your great experience, to be involved in this profound change.

But the most profound changes are in the new 18th District.